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OCR: sis within The major pathways of steroid biosynth emphasise the human adrenal cortex (see Fig. 7.12) lity of the crucial dependence upon the availal role which specific enzyme systems. Given the vita etabolism, adrenocortical steroids play in human n iciency in it is not surprising that even a partial de rious the activity of these enzymes produces s metabolic disturbance, Clinical syndrom he corresponding to deficiencies of each of scribed and enzymes that are involved have been de enital are referred to as different forms of cong adrenal hyperplasia.